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A DVD player with movies, a new fairly quiet toy so others are not disturbed seem to be winners. With that said our son cried (actually screamed) for 23 hours straight on two planes a a fairly lenthy layover (all with my DH as he travelled to get him alone). He was exhausted, had a cold, and the best thing would could have done for him was to give him the benedryl that I had packed so he sould rest (DH checked it and didn't put it into the carry on, which he regrets now). It made his homecoming traumatic for him as well as my DH and actually affected their bonding. FYI I am not usually in favor of medicating for these reasons.
If you don't feel comfortable medicating your children don't do it. But maybe find out the dosage in accordance with their weight just in case. Best of luck!
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