This verse is always encouraging, but we had one period of time where I was very overwhelmed with our circumstances and this verse became the one focal point that I could concentrate on each day.
My mother had died 6 months previously, my sister was dx'd with breast cancer the day before my mom's funeral, a month after mom died, my grandmother had died. We had 3 children of our own, 2 with special needs. We were fostering 2 children who had been severely neglected and had major developmental delays as well as attachment problems. We were caring for my grandfather while my sister, who normally cares for my grandfather, was having radiation treatments for her cancer. Needless to say, every morning I dreaded getting up! There was just no way I could continue on...in my own strength, anyway. I clung to this verse like a barnacle!
Things levelled off; I requested that the foster kids be moved, my sister came back from cancer treatment and my grandfather went home...so things DID get better. Eventually.
But I know I would have had a nervous breakdown (literally) if God had not sustained me, as He always does, of course!
This has remained one of my favorite verses, particularly as it was from one of my mom's favorite books in the Bible.