I've never flown business class -- we were in coach for both of our adoptions. The flights are always stressful and crowded, and if you're adopting infants/toddlers there's a lot of "stuff" you need on the plane.
If you have the miles, I definitely think it would be a great way to treat yourself. You can survive in coach, of course (we did and it wasn't *that* bad) but it sure would be nice to be in business class.
