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My opinion is thus: Do NOT withhold any more than you need to to cover your normal liability. There is no good reason to give the IRS an interest-free loan throughout the year. It's your money. If you consider your "tax refund" as a form of savings; have some money that you know you will not miss automatically deducted from your checking account each month and have it flow into a "high" interest bearing account with ING, ETrade, or simliar. (I do this for both savings and to cover local earned income taxes that I cannot get withheld)
Adoption is a special case and I suggest you do not adjust your withholding to reflect any anticipated tax benefits...the reason being you have no assurance of the timing and you cannot begin to claim the credit until you actually complete your adoption. There is too much that can affect the "when" of that completion. Nor can you fully anticipate what your credit will be for a given year until you do your taxes. Remember, it's a credit against taxes owed, not a "check" for ten grand. And in some cases, you may need to take it over several years, depending on your tax liablities.
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